I'm wondering if you thought the show handled it well after all, since the episode has been getting a lot of complaints from people with Asperger's.
Has it? I surfed over to one of the forums (where I....used to post, a long time ago...ahem) on the subject and read some comments the night it aired, but didn't look too deeply. It seemed non-fans of the show who happened to tune in were sort of offended, while regular viewers were amused.
I thought it was fine, though disappointing in the sense that they didn't really do very much with it. The Asperger's characters were really over-the-top, but that's South Park, and since they're just faking it anyway it didn't bother me. It wasn't portrayed as "real," the way Grey's Anatomy and Law and Order are meant to be taken at face-value. The Tourrette's episode was definitely better, but I enjoyed what little there was.
A couple things I really dug, though:
-The whole "we see the world as it REALLY is" thing. I have no idea how intentional this was, but the thing is, a lot of people on the spectrum really believe this, that their social disorder actually makes them more capable of seeing the world the right way, or that it's just a different, equally valid way of seeing the world. I won't get into my thoughts on this these days, but I thought the (possible) allusion to that, taken very literally, was quite funny.
-The vaccination stuff. Although again not nearly enough was done with it, Matt and Trey appeared to be observing (correctly) that the controversy over the vaccines is fairly silly, and often applied to people who aren't really autistic at all. Good on them.
I don't know what the gist of the complaints has been, though.